Walter Lab

Michael Schoof

Scientific Interest

Molecular mechanisms of aging; Pharmacological modulation of aging and aging-associated phenotypes

Current Research Interests

Understanding how regulation of the integrated stress response impacts memory

Former Lab Affiliations

2011-2012 Dr. Carrie Rinker-Schaeffer, University of Chicago, Chicago IL
2012-2016 Dr. Anne Brunet, Stanford University, Stanford CA
2013 Dr. Richard Morimoto, Northwestern University, Evanston IL
2016-2017 Dr. Julie Ahringer, University of Cambridge Gurdon Institute, Cambridge UK

 

Education

2012-2016 B.S. Molecular, Cellular, and Developmental Biology –
Stanford University, Stanford CA
2016-2017 MPhil Genetics – University of Cambridge, Churchill College, Cambridge UK

 

Selected Publications

Schoof M, Boone M, Wang L, Lawrence R, Frost A, Walter P. eIF2B conformation and assembly state regulate the integrated stress response. eLife 10:e65703, 2021
(PMID : 33688831) (PDF)
Schoof M, Faust B, Saunders RA, Sangwan S, Rezelj V, Hoppe N, Boone M, Billesbølle CB, Puchades C, Azumaya CM, Kratochvil HT, Zimanyi M, Deshpande I, Liang J, Dickinson S, Nguyen HC, Chio CM, Merz GE, Thompson MC, Diwanji D, Schaefer K, Anand AA, Dobzinski N, Zha BS, Simoneau CR, Leon K, White KM, Chio US, Gupta M, Jin M, Li F, Liu Y, Zhang K, Bulkley D, Sun M, Smith AM, Rizo AN, Moss F, Brilot AF, Pourmal S, Trenker R, Pospiech T, Gupta S, Barsi-Rhyne B, Belyy V, Barile-Hill AW, Nock S, Liu Y, Krogan NJ, Ralston CY, Swaney DL, García-Sastre A, Ott M, Vignuzzi M, QCRG Structural Biology Consortium, Walter P, Manglik A. An ultra-potent synthetic nanobody neutralizes SARS-CoV-2 by stabilizing inactive Spike. Science. 10.1126/science.abe3255, 2020
(PMID : 33154106) (PDF)