Walter Lab

  • Walter Lab
  • Research
    • The Unfolded Protein Response and IRE1 Signaling in Health and Disease
    • Organellar quality control, dynamics, and inheritance
    • RNA processing in the unfolded protein response
    • The integrated stress response and its role in cognition
    • ATF6-branch signaling through regulated proteolysis
  • Lab Members
    • Current
    • Alumni
  • Contact Us
  • Social
  • Publications
  • News & Notes

Morgane Boone

Alumni Postdoctoral Fellow

morgane@walterlab.ucsf.edu
Scientific Interest

The eukaryotic secretory system, protein folding stress, neurodegeneration, omics technologies 

Current Research Interests

Modulation of translation by the Integrated Stress Response in the brain

Former Lab Affiliations

2009 – 2010 Prof. Nico Callewaert – Master student, VIB/Ghent University
2010 – 2017 Prof. Nico Callewaert – Ph.D. student, VIB/Ghent University

Education

2005 – 2008  B. S. in Biochemistry & Biotechnology, Ghent University, Belgium
2008 – 2010 M.S. in Biochemistry & Biotechnology, Ghent University, Belgium
2010 – 2017 Ph.D. in Biochemistry & Biotechnology, Ghent University, Belgium

Selected Publications

Schoof M, Boone M, Wang L, Lawrence R, Frost A, Walter P. eIF2B conformation and assembly state regulate the integrated stress response. eLife 10:e65703, 2021
(PMID : 33688831) (PDF)
Ramundo S, Asakura Y, Salomé PA, Strenkert D, Boone M, Mackinder LCM, Takafuji K, Dinc E, Rahire M, Crèvecoeur M, Magneschi L, Schaad O, Hippler M, Jonikas MC, Merchant S, Nakai M, Rochaix J-D, Walter P. Co-expressed subunits of dual genetic origin define a conserved supercomplex mediating essential protein import into chloroplasts. Proc Natl Acad Sci. 202014294, 2020
(PMID : 33273113) (PDF)
Krukowski K, Nolan A, Frias ES, Boone M, Ureta G, Grue K, Paladini M-S, Elizarraras E, Delgado L, Bernales S, Walter P, Rosi S. Small molecule cognitive enhancer reverses age-related memory decline in mice. eLife 9:e62048, 2020
(PMCID : PMC7721440) (PMID : 33258451) (PDF)
Schoof M, Faust B, Saunders RA, Sangwan S, Rezelj V, Hoppe N, Boone M, Billesbølle CB, Puchades C, Azumaya CM, Kratochvil HT, Zimanyi M, Deshpande I, Liang J, Dickinson S, Nguyen HC, Chio CM, Merz GE, Thompson MC, Diwanji D, Schaefer K, Anand AA, Dobzinski N, Zha BS, Simoneau CR, Leon K, White KM, Chio US, Gupta M, Jin M, Li F, Liu Y, Zhang K, Bulkley D, Sun M, Smith AM, Rizo AN, Moss F, Brilot AF, Pourmal S, Trenker R, Pospiech T, Gupta S, Barsi-Rhyne B, Belyy V, Barile-Hill AW, Nock S, Liu Y, Krogan NJ, Ralston CY, Swaney DL, García-Sastre A, Ott M, Vignuzzi M, QCRG Structural Biology Consortium, Walter P, Manglik A. An ultra-potent synthetic nanobody neutralizes SARS-CoV-2 by stabilizing inactive Spike. Science. 10.1126/science.abe3255, 2020
(PMID : 33154106) (PDF)
Perlaza K, Toutkoushian H, Boone M, Lam M, Iwai M, Jonikas MC, Walter P, Ramundo S. The Mars1 kinase confers photoprotection through signaling in the chloroplast unfolded protein response. eLife 8:e49577, 2019
(PMID : 31612858) (PDF)

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