Walter Lab

Silke Nock

Current Research Interests

Creating and supporting the framework for good science.

Former Lab Affiliations

Prof. Dr. Mathias Sprinzl, Department of Biochemistry, University of Bayreuth
Department of Clinical Microbiology, University of Erlangen

Education

Masters Clinical Microbiology, Histology, Haematology, and Clinical Chemistry – Technical Medicine, Klinikum Bayreuth, Germany
M.Sc Biochemistry, University of San Francisco, USA

Selected Publications

Schoof M, Faust B, Saunders RA, Sangwan S, Rezelj V, Hoppe N, Boone M, Billesbølle CB, Puchades C, Azumaya CM, Kratochvil HT, Zimanyi M, Deshpande I, Liang J, Dickinson S, Nguyen HC, Chio CM, Merz GE, Thompson MC, Diwanji D, Schaefer K, Anand AA, Dobzinski N, Zha BS, Simoneau CR, Leon K, White KM, Chio US, Gupta M, Jin M, Li F, Liu Y, Zhang K, Bulkley D, Sun M, Smith AM, Rizo AN, Moss F, Brilot AF, Pourmal S, Trenker R, Pospiech T, Gupta S, Barsi-Rhyne B, Belyy V, Barile-Hill AW, Nock S, Liu Y, Krogan NJ, Ralston CY, Swaney DL, García-Sastre A, Ott M, Vignuzzi M, QCRG Structural Biology Consortium, Walter P, Manglik A. An ultra-potent synthetic nanobody neutralizes SARS-CoV-2 by stabilizing inactive Spike. Science. 10.1126/science.abe3255, 2020
(PMID : 33154106) (PDF)
Peluso P, Shan S, Nock S, Herschlag D, Walter P. Role of SRP RNA in the GTPase cycles of Ffh and FtsY. Biochemistry 40:15224-33, 2001
(PMID : 11735405) (PDF)
Nock S, Gonzalez TN, Sidrauski C, Niwa M, Walter P. Purification and activity assays of the catalytic domains of the kinase/endoribonuclease Ire1p from Saccharomyces cerevisiae. Meth Enzymol 342:3-10, 2001
(PMID : 11586903) (PDF)
Peluso P, Herschlag D, Nock S, Freymann DM, Johnson AE, Walter P. Role of 4.5S RNA in assembly of the bacterial signal recognition particle with its receptor. Science 288:1640-3, 2000
(PMID : 10834842) (PDF)
Gonzalez TN, Sidrauski C, Nock S, Walter P. Mechanism of non-spliceosomal mRNA splicing in the unfolded protein response pathway. EMBO J. 11:3119-32, 1999
(PMCID : 1171393) (PMID : 10357823) (PDF)