Notice: Function _load_textdomain_just_in_time was called incorrectly. Translation loading for the wordpress-seo domain was triggered too early. This is usually an indicator for some code in the plugin or theme running too early. Translations should be loaded at the init action or later. Please see Debugging in WordPress for more information. (This message was added in version 6.7.0.) in /nas/content/live/wlabdemo/wp-includes/functions.php on line 6114

Notice: Function _load_textdomain_just_in_time was called incorrectly. Translation loading for the genesis domain was triggered too early. This is usually an indicator for some code in the plugin or theme running too early. Translations should be loaded at the init action or later. Please see Debugging in WordPress for more information. (This message was added in version 6.7.0.) in /nas/content/live/wlabdemo/wp-includes/functions.php on line 6114

Notice: Function _load_textdomain_just_in_time was called incorrectly. Translation loading for the outreach domain was triggered too early. This is usually an indicator for some code in the plugin or theme running too early. Translations should be loaded at the init action or later. Please see Debugging in WordPress for more information. (This message was added in version 6.7.0.) in /nas/content/live/wlabdemo/wp-includes/functions.php on line 6114
Morgane Boone - Walter Lab

Walter Lab

Morgane Boone

Alumni Postdoctoral Fellow

morgane@walterlab.ucsf.edu
Scientific Interest

The eukaryotic secretory system, protein folding stress, neurodegeneration, omics technologies 

Current Research Interests

Modulation of translation by the Integrated Stress Response in the brain

Former Lab Affiliations

2009 – 2010 Prof. Nico Callewaert – Master student, VIB/Ghent University
2010 – 2017 Prof. Nico Callewaert – Ph.D. student, VIB/Ghent University

Education

2005 – 2008  B. S. in Biochemistry & Biotechnology, Ghent University, Belgium
2008 – 2010 M.S. in Biochemistry & Biotechnology, Ghent University, Belgium
2010 – 2017 Ph.D. in Biochemistry & Biotechnology, Ghent University, Belgium

Selected Publications

Schoof M, Boone M, Wang L, Lawrence R, Frost A, Walter P. eIF2B conformation and assembly state regulate the integrated stress response. eLife 10:e65703, 2021
(PMID : 33688831) (PDF)
Ramundo S, Asakura Y, Salomé PA, Strenkert D, Boone M, Mackinder LCM, Takafuji K, Dinc E, Rahire M, Crèvecoeur M, Magneschi L, Schaad O, Hippler M, Jonikas MC, Merchant S, Nakai M, Rochaix J-D, Walter P. Co-expressed subunits of dual genetic origin define a conserved supercomplex mediating essential protein import into chloroplasts. Proc Natl Acad Sci. 202014294, 2020
(PMID : 33273113) (PDF)
Krukowski K, Nolan A, Frias ES, Boone M, Ureta G, Grue K, Paladini M-S, Elizarraras E, Delgado L, Bernales S, Walter P, Rosi S. Small molecule cognitive enhancer reverses age-related memory decline in mice. eLife 9:e62048, 2020
(PMCID : PMC7721440) (PMID : 33258451) (PDF)
Schoof M, Faust B, Saunders RA, Sangwan S, Rezelj V, Hoppe N, Boone M, Billesbølle CB, Puchades C, Azumaya CM, Kratochvil HT, Zimanyi M, Deshpande I, Liang J, Dickinson S, Nguyen HC, Chio CM, Merz GE, Thompson MC, Diwanji D, Schaefer K, Anand AA, Dobzinski N, Zha BS, Simoneau CR, Leon K, White KM, Chio US, Gupta M, Jin M, Li F, Liu Y, Zhang K, Bulkley D, Sun M, Smith AM, Rizo AN, Moss F, Brilot AF, Pourmal S, Trenker R, Pospiech T, Gupta S, Barsi-Rhyne B, Belyy V, Barile-Hill AW, Nock S, Liu Y, Krogan NJ, Ralston CY, Swaney DL, García-Sastre A, Ott M, Vignuzzi M, QCRG Structural Biology Consortium, Walter P, Manglik A. An ultra-potent synthetic nanobody neutralizes SARS-CoV-2 by stabilizing inactive Spike. Science. 10.1126/science.abe3255, 2020
(PMID : 33154106) (PDF)
Perlaza K, Toutkoushian H, Boone M, Lam M, Iwai M, Jonikas MC, Walter P, Ramundo S. The Mars1 kinase confers photoprotection through signaling in the chloroplast unfolded protein response. eLife 8:e49577, 2019
(PMID : 31612858) (PDF)