Alexei Korennykh
Alumni Postdoc
Selected Publications
- Mendez A, Alfaro J, Morales-Soto MA, Dar AC, McCullagh E, Gotthardt K, Li H, Acosta-Alvear D, Sidrauski C, Korennykh AV, Bernales S, Shokat KM, Walter P. Endoplasmic reticulum stress-independent activation of unfolded protein response kinases by a small molecule ATP-mimic. eLife 4:e07314, 2015
- van Anken E, Pincus D, Coyle S, Aragón T, Osman C, Lari F, Puerta S, Korennykh A, Walter P. Specificity in endoplasmic reticulum-stress signaling in yeast entails a step-wise engagement of HAC1 mRNA to clusters of the stress sensor Ire1. eLife 3:e05031, 2014
- Korennykh A, Walter P. Structural basis of the unfolded protein response. Annu Rev Cell Dev Biol 28:251-77, 2012
- Korennykh A, Egea P, Korostelev A, Finer-Moore J, Stroud R, Zhang C, Shokat K, Walter P. Cofactor-mediated conformational control in the bifunctional kinase/RNase Ire1. BMC Biol 9:48, 2011
- Korennykh A, Korostelev A, Egea P, Finer-Moore J, Stroud R, Zhang C, Shokat K, Walter P. Structural and functional basis for RNA cleavage by Ire1. BMC Biol 9:47, 2011
- Rubio C, Pincus D, Korennykh A, Schuck S, El-Samad H, Walter P. Homeostatic adaptation to endoplasmic reticulum stress depends on Ire1 kinase activity. J Cell Biol 193:171-84, 2011
- Li H, Korennykh AV, Behrman SL, Walter P. Mammalian endoplasmic reticulum stress sensor IRE1 signals by dynamic clustering. Proc Natl Acad Sci 107:16113–18, 2010
- Aragón T, van Anken E, Pincus D, Serafimova IM, Korennykh AV, Rubio CA, Walter P. Messenger RNA targeting to endoplasmic reticulum stress signalling sites. Nature 457:736-40, 2009
- Korennykh A, Egea P, Korostelev A, Finer-Moore J, Zhang C, Shokat K, Stroud R, Walter P. The unfolded protein response signals through high-order assembly of Ire1. Nature 457:687-93, 2008