David Pincus
Alumni Graduate Student
Selected Publications
- Pincus D, Aranda-Díaz A, Zuleta IA, Walter P, El-Samad H. Delayed Ras/PKA signaling augments the unfolded protein response. Proc Natl Acad Sci 111:14800-5, 2014
- van Anken E, Pincus D, Coyle S, Aragón T, Osman C, Lari F, Puerta S, Korennykh A, Walter P. Specificity in endoplasmic reticulum-stress signaling in yeast entails a step-wise engagement of HAC1 mRNA to clusters of the stress sensor Ire1. eLife 3:e05031, 2014
- Gardner B, Pincus D, Gotthardt K, Gallagher C, Walter P. Endoplasmic reticulum stress sensing in the unfolded protein response. Cold Spring Harb Perspect Biol 5:a013169, 2013
- Fordyce P, Pincus D, Kimmig P, Nelson C, El-Samad H, Walter P, DeRisi J. Basic leucine zipper transcription factor Hac1 binds DNA in two distinct modes as revealed by microfluidic analyses. Proc Nat Acad Sci 109:3084-93, 2012
- Pincus D, Walter P. A first line of defense against ER stress. J Cell Biol 198:277-9, 2012
- Rubio C, Pincus D, Korennykh A, Schuck S, El-Samad H, Walter P. Homeostatic adaptation to endoplasmic reticulum stress depends on Ire1 kinase activity. J Cell Biol 193:171-84, 2011
- Pincus D, Chevalier MW, Aragón T, van Anken E, Vidal SE, El-Samad H, Walter P. BiP binding to the ER-stress sensor Ire1 tunes the homeostatic behavior of the unfolded protein response. PLoS Biol 8:e1000415, 2010
- Aragón T, van Anken E, Pincus D, Serafimova IM, Korennykh AV, Rubio CA, Walter P. Messenger RNA targeting to endoplasmic reticulum stress signalling sites. Nature 457:736-40, 2009