Le Thomas A, Ferri E, Marsters S, Harnoss JM, Lawrence DA, Zuazo-Gaztelu I, Modrusan Z, Chan S, Solon M, Chalouni C, Li W, Koeppen H, Rudolph J, Wang W, Wu TD, Walter P, Ashkenazi A. Decoding non-canonical mRNA decay by the endoplasmic-reticulum stress sensor IRE1α. Nat Comms DOI: 10.1038/s41467-021-27597-7, 2021
(PMID: not available) (PDF)
Belyy V, Zuazo-Gaztelu I, Alamban A, Ashkenazi A, Walter P. Endoplasmic reticulum stress activates human IRE1α through reversible assembly of inactive dimers into small oligomers. bioRxiv https://www.biorxiv.org/content/10.1101/2021.09.29.462487v1, 2021
(PMID: not available) (PDF)
Tran NH *, Carter SD *, De Mazière A, Ashkenazi A, Klumperman J, Walter P *, Jensen GJ *. The stress-sensing domain of activated IRE1α forms helical filaments in narrow ER membrane tubes. Science 374:52-57, 2021
(PMID: 34591618) (PDF)
Harnoss JM, Le Thomas A, Shemorry A, Marsters SA, Lawrence DA, Lu M, Chen Y-C A, Qing J, Totpal K, Kan D, Segal E, Merchant M, Reichelt M, Ackerly Wallweber H, Wang W, Clark K, Kaufman S, Beresini MH, Laing ST, Sandoval W, Lorenzo M, Wu J, Ly J, De Bruyn T, Heidersbach A, Haley B, Gogineni A, Weimer RM, Lee D, Braun M-G, Rudolph J, VanWyngarden MJ, Sherbenou DW, Gomez-Bougie P, Amiot M, Acosta-Alvear D, Walter P, Ashkenazi A. Disruption of IRE1α through its kinase domain attenuates multiple myeloma. Proc Natl Acad Sci 116:16420-16429, 2019
(PMID: 31371506) (PDF)
Lu M, Lawrence D, Marsters S, Acosta-Alvear D, Kimmig P, Mendez A, Paton A, Paton J, Walter P, Ashkenazi A. Opposing unfolded-protein-response signals converge on death receptor 5 to control apoptosis. Science 345:98-101, 2014
(PMID: 24994655) (PDF)
Peluso P, Shan S, Nock S, Herschlag D, Walter P. Role of SRP RNA in the GTPase cycles of Ffh and FtsY. Biochemistry 40:15224-33, 2001
(PMID: 11735405) (PDF)
Peluso P, Herschlag D, Nock S, Freymann DM, Johnson AE, Walter P. Role of 4.5S RNA in assembly of the bacterial signal recognition particle with its receptor. Science 288:1640-3, 2000
(PMID: 10834842) (PDF)
Schmitz U, Behrens S, Freymann D, Keenan R, Lukavsky P, Walter P, James T. Structure of the phylogenetically most conserved domain of SRP RNA. RNA 5:1419-29, 1999
(PMID: 10580470) (PDF)
Schmitz U, James T, Lukavsky P, Walter P. Structure of the most conserved internal loop in SRP RNA. Nat Struct Biol 6:634-8, 1999
(PMID: 10404218) (PDF)
