Jonathan Lin

Yildirim Z, Baboo S, Hamid SM, Dogan AE, Tufanli O, Robichaud S, Emerton C, Diedrich JK, Vatandaslar H, Nikolos F, Gu Y, Iwawaki T, Tarling E, Ouimet M, Nelson DL, Yates JR 3rd, Walter P, Erbay E. Intercepting IRE1 kinase-FMRP signaling prevents atherosclerosis progression. EMBO Mol Med 14(4):e15344, 2022
(PMID: 35191199) (PDF)

Li W, Crotty K, Garrido Ruiz D, Voorhies M, Rivera C, Sil A, Mullins RD, Jacobson MP, Peschek J, Walter P. Protomer alignment modulates specificity of RNA substrate recognition by Ire1. eLife 10:e6742, 2021
(PMID: 33904404) (PDF)

Li W, Crotty K, Ruiz DG, Voorhies M, Rivera C, Sil A, Mullins RD, Jacobson MP, Peschek J, Walter P. Protomer alignment modulates specificity of RNA substrate recognition by Ire1. bioRxiv doi: https://doi.org/10.1101/2021.02.10.430655, 2021
(PMID: not available) (PDF)

Walter P, Mullins RD. To fight Covid-19, open access to scientific publishing. STAT, available online, 2020
(PMID: not available) 

Carter SD, Hampton CM, Langlois R, Melero R, Farino ZJ, Calderon MJ, Li W, Wallace CT, Tran NH, Grassucci RA, Siegmund SE, Pemberton J, Morgenstern TJ, Eisenman L, Aguilar JI, Greenberg NL, Levy ES, Yi E, Mitchell WG, Rice WJ, Wigge C, Pilli J, George EW, Aslanoglou D, Courel M, Freyberg RJ, Javitch JA, Wills ZP, Area-Gomez E, Shiva S, Bartolini F, Volchuk A, Murray SA, Aridor M, Fish KN, Walter P, Balla T, Fass D, Wolf SG, Watkins SC, Carazo JM, Jensen GJ, Frank J, Freyberg Z. Ribosome-associated vesicles: A dynamic subcompartment of the endoplasmic reticulum in secretory cells. Sci Adv 6:eaay9572, 2020
(PMID: 32270040) (PDF)

Zhu PJ, Khatiwada S, Cui Y, Reineke LC, Dooling SW, Kim JJ, Li Wei, Walter P, Costa-Mattioli M. Activation of the ISR mediates the behavioral and neurophysiological abnormalities in Down syndrome. Science 366:843-849, 2019
(PMID: 31727829) (PDF)

Walter P, Mullins D. From symbiont to parasite: the evolution of for-profit science publishing. Mol. Biol. Cell. 30:2537-2542, 2019
(PMID: 31539315) (PDF)

Kornmann B, Currie E, Collins S, Schuldiner M, Nunnari J, Weissman J, Walter P. An ER-mitochondria tethering complex revealed by a synthetic biology screen. Science 325:477-81, 2009
(PMID: 19556461) (PDF)

Hollien J, Lin J, Li H, Stevens N, Walter P, Weissman J. Regulated Ire1-dependent decay of messenger RNAs in mammalian cells. J Cell Biol 186:323-31, 2009
(PMID: 19651891) (PDF)

Jonikas M, Collins S, Denic V, Oh E, Quan E, Schmid V, Weibezahn J, Schwappach B, Walter P, Weissman J, Schuldiner M. Comprehensive characterization of genes required for protein folding in the endoplasmic reticulum. Science 323:1693-7, 2009
(PMID: 19325107) (PDF)

Lisbona F, Rojas-Rivera D, Thielen P, Zamorano S, Todd D, Martinon F, Glavic A, Kress C, Lin J, Walter P, Reed J, Glimcher L, Hetz C. BAX inhibitor-1 is a negative regulator of the ER stress sensor IRE1alpha. Mol Cell 33:679-91, 2009
(PMID: 19328063) (PDF)

Lin J, Li H, Zhang Y, Ron D, Walter P. Divergent effects of PERK and IRE1 signaling on cell viability. PLoS ONE 4:e4170, 2009
(PMID: 19137072) (PDF)

Walther T, Aguilar P, Fröhlich F, Chu F, Moreira K, Burlingame A, Walter P. Pkh-kinases control eisosome assembly and organization. EMBO J 26:4946-55, 2007
(PMID: 18034155) (PDF)

Lin J, Li H, Yasumura D, Cohen H, Zhang C, Panning B, Shokat K, Lavail M, Walter P. IRE1 signaling affects cell fate during the unfolded protein response. Science 318:944-9, 2007
(PMID: 17991856) (PDF)

Chu F, Shan S, Moustakas D, Alber F, Egea P, Stroud R, Walter P, Burlingame A. Unraveling the interface of signal recognition particle and its receptor by using chemical cross-linking and tandem mass spectrometry. Proc Natl Acad Sci 101:16454-9, 2004
(PMID: 15546976) (PDF)

Selinger D, Brennwald P, Althoff S, Reich C, Hann B, Walter P, Wise J. Genetic and biochemical analysis of the fission yeast ribonucleoprotein particle containing a homolog of Srp54p. Nucleic Acids Res 22:2557-67, 1994
(PMID: 8041618) (PDF)

Brown J, Hann B, Medzihradszky K, Niwa M, Burlingame A, Walter P. Subunits of the Saccharomyces cerevisiae signal recognition particle required for its functional expression. EMBO J 13:4390-400, 1994
(PMID: 7925282) (PDF)

Wolin S, Walter P. Discrete nascent chain lengths are required for the insertion of presecretory proteins into microsomal membranes. J Cell Biol 121:1211-9, 1993
(PMID: 8389768) (PDF)

Hann B, Stirling C, Walter P. SEC65 gene product is a subunit of the yeast signal recognition particle required for its integrity. Nature 356:532-3, 1992
(PMID: 1313947) (PDF)

Andrews D, Lauffer L, Walter P, Lingappa V. Evidence for a two-step mechanism involved in assembly of functional signal recognition particle receptor. J Cell Biol 108:797-810, 1989
(PMID: 2537835) (PDF)

Wolin S, Walter P. Signal recognition particle mediates a transient elongation arrest of preprolactin in reticulocyte lysate. J Cell Biol 109:2617-22, 1989
(PMID: 2556403) (PDF)

Wolin S, Walter P. Ribosome pausing and stacking during translation of a eukaryotic mRNA. EMBO J 7:3559-69, 1988
(PMID: 2850168) (PDF)

Lingelbach K, Zwieb C, Webb J, Marshallsay C, Hoben P, Walter P, Dobberstein B. Isolation and characterization of a cDNA clone encoding the 19 kDa protein of signal recognition particle (SRP): expression and binding to 7SL RNA. Nucleic Acids Res 16:9431-42, 1988
(PMID: 2460823) (PDF)

Walter P, Lingappa V. Mechanism of protein translocation across the endoplasmic reticulum membrane. Annu Rev Cell Biol 2:499-516, 1986
(PMID: 3030381) (PDF)

Walter P, Jackson R, Marcus M, Lingappa V, Blobel G. Tryptic dissection and reconstitution of translocation activity for nascent presecretory proteins across microsomal membranes. Proc Natl Acad Sci 76:1795-9, 1979
(PMID: 109833) (PDF)

Blobel G, Walter P, Chang C, Goldman B, Erickson A, Lingappa V. Translocation of proteins across membranes: the signal hypothesis and beyond. Symp Soc Exp Biol 33:9-36, 1979
(PMID: 524275)