Mable Lam

Alumni Postdoctoral Fellow

mable@walterlab.ucsf.edu

Scientific Interest

Signal transduction, regulation of stress response pathways

Current Research Interests

Understanding how Ire1 activity is tuned to ER stress through oligomerization

Former Lab Affiliations

2010	– Summer AMGEN Undergraduate Researcher, Stanford University

Education

2008-2012	BA Chemistry – Amherst College,
2012-2019	PhD – University of California, San Francisco,

Selected Publications

Lam M, Marsters S, Ashkenazi A, Walter P. Misfolded proteins bind and activate death receptor 5 to induce apoptosis during unresolved endoplasmic reticulum stress. eLife 9:e52291, 2020
(PMCID : PMC7041945) (PMID : 1904339) (PDF)

Perlaza K, Toutkoushian H, Boone M, Lam M, Iwai M, Jonikas MC, Walter P, Ramundo S. The Mars1 kinase confers photoprotection through signaling in the chloroplast unfolded protein response. eLife 8:e49577, 2019
(PMID : 31612858) (PDF)