Ciara Gallagher

Torres SE, Gallagher CM, Plate L, Gupta M, Liem CR, Guo X, Tian R, Stroud RM, Kampmann M, Weissman JS, Walter P. Ceapins block the unfolded protein response sensor ATF6α by inducing a neomorphic inter-organelle tether. eLife 8:e46595, 2019
(PMID : 31149896) (PDF)

Gallagher C, Garri C, Cain E, Ang K, Wilson C, Chen S, Hearn B, Jaishankar P, Aranda-Diaz A, Arkin M, Renslo A, Walter P. Ceapins are a new class of unfolded protein response inhibitors, selectively targeting the ATF6α branch. eLife 5:e11878, 2016
(PMCID : 4954757) (PMID : 27435960) (PDF)

Gallagher C, Walter P. Ceapins inhibit ATF6α signaling by selectively preventing transport of ATF6α to the Golgi apparatus during ER stress. eLife 5:e11880, 2016
(PMCID : 4954756) (PMID : 27435962) (PDF)

Plate L, Cooley C, Chen J, Paxman R, Gallagher C, Madoux F, Genereux J, Dobbs W, Garza D, Spicer T, Scampavia L, Brown S, Rosen H, Powers E, Walter P, Hodder P, Wiseman L, Kelly J. Small molecule proteostasis regulators that reprogram the ER to reduce extracellular protein aggregation. eLife 5:e15550, 2016
(PMCID : 4954754) (PMID : 27435961) (PDF)

Sidrauski C, Acosta-Alvear D, Khoutorsky A, Vedantham P, Hearn B, Li H, Gamache K, Gallagher C, Ang K, Wilson C, Okreglak V, Ashkenazi A, Hann B, Nader K, Arkin M, Renslo A, Sonenberg N, Walter P. Pharmacological brake-release of mRNA translation enhances cognitive memory. eLife 2:e00498, 2013
(PMCID : PMC3667625) (PMID : 23741617) (PDF)

Gardner B, Pincus D, Gotthardt K, Gallagher C, Walter P. Endoplasmic reticulum stress sensing in the unfolded protein response. Cold Spring Harb Perspect Biol 5:a013169, 2013
(PMCID : PMC3578356) (PMID : 23388626) (PDF)