Walter Lab

  • Walter Lab
  • Research
    • The Unfolded Protein Response and IRE1 Signaling in Health and Disease
    • Organellar quality control, dynamics, and inheritance
    • RNA processing in the unfolded protein response
    • The integrated stress response and its role in cognition
    • ATF6-branch signaling through regulated proteolysis
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    • Alumni
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Voytek Okreglak


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Alumni Postdoctoral Fellow

voytek@walterlab.ucsf.edu

Scientific Interest

Tail-anchored protein targeting and membrane protein quality control

Current Research Interests

Characterization of quality control pathways acting on mistargeted tail-anchored proteins

Former Lab Affiliations

1999-2001 Professor Jodi Nunnari – Undergraduate Researcher, University of California, Davis
2001-2003 Professor Jodi Nunnari – Post-graduate Researcher, University of California, Davis
2003-2009 Dr. David Drubin – Graduate Student, University of of California, Berkeley
2009-2010 Dr. David Drubin – Post-doctoral Researcher, University of California, Berkeley
2010-Present Dr. Peter Walter – Post-doctoral Researcher, University of California, San Francisco

Education

2001 B.S. Biochemistry – University of California, Davis, USA
2009 Ph.D Cell Biology – University of California, Berkeley, USA

Selected Publications

Rao M, Okreglak V, Chio US, Cho H, Walter P, Shan SO. Multiple selection filters ensure accurate tail-anchored membrane protein targeting. eLife 5:e21301, 2016
(PMCID : 5214336) (PMID : 27925580) (PDF)
Osman C, Noriega T, Okreglak V, Fung J, Walter P. Integrity of the yeast mitochondrial genome, but not its distribution and inheritance, relies on mitochondrial fission and fusion. Proc Nat Acad Sci 112:947-56, 2015
(PMCID : PMC4352819) (PMID : 25730886) (PDF)
Okreglak V, Walter P. The conserved AAA-ATPase Msp1 confers organelle specificity to tail-anchored proteins. Proc Nat Acad Sci 111:8019–8024, 2014
(PMCID : PMC4050615) (PMID : 24821790) (PDF)
Sidrauski C, Acosta-Alvear D, Khoutorsky A, Vedantham P, Hearn B, Li H, Gamache K, Gallagher C, Ang K, Wilson C, Okreglak V, Ashkenazi A, Hann B, Nader K, Arkin M, Renslo A, Sonenberg N, Walter P. Pharmacological brake-release of mRNA translation enhances cognitive memory. eLife 2:e00498, 2013
(PMCID : PMC3667625) (PMID : 23741617) (PDF)

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