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Scientific Interest

When the unfolded protein response (UPR) is activated, global synthesis of proteins is shut down to stem the flux of new proteins into the endoplasmic reticulum (ER). However, during this shut down, a subset of proteins is instead preferentially translated. I am interested in studying the mechanisms by which preferential translation is achieved, and also other modes of translation regulation involved in ER stress.

Former Lab Affiliations

2010-2013

Dr. Jamie Cate – Undergraduate Researcher, University of California, Berkeley

Education

2008-2012	B.S. Chemical Biology – University of California, Berkeley, USA
2013-Present	Ph.D – University of California, San Francisco, USA

Scientific Interest

I am a joint student between the Walter and Douglas labs. I am interested in exploring applications of DNA nanotechnology in structural studies of proteins in the Unfolded Protein Response (UPR).

Current Research Interests

(1) Defining oligomeric state of IRE1 using DNA origami. (2) Structural studies of the UPR effector Hac1 with electron cryo-microscopy.

Former Lab Affiliations

2010-2013	Dr. Lionel Cheruzel – Undergraduate Student, San Jose State University
2012	Dr. Iswar Hariharan – Amgen Scholars Summer Student, University of California, Berkeley

Education

2013	B.S. Biological Sciences – San Jose State University, USA
2013-Present	Ph.D. – University of California, San Francisco, USA