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Elif Karagöz

Elif Karagöz

Alumni Postdoctoral Fellow

elif@walterlab.ucsf.edu

Current Position

Group Leader
Max F. Perutz Laboratories
University of Vienna
Dr. Bohr-Gasse 9, 1030 Vienna | Room: 3.507/ 3.508
elif.karagoez@univie.ac.at

Scientific Interest

Understanding the working principles of proteins, especially the ones involved in protein folding and stress response pathways

Current Research Interests

The recognition of unfolded proteins by Ire1’s sensor domain and its regulation by the ER-chaperone BiP.

Former Lab Affiliations

2006 Dr. Reinhard Lührmann – Master Student, Max Planck for Biophysical Chemistry
2006-2011 Dr. Stefan Rüdiger – Ph.D Student, Utrecht University

Education

2004 B.S. Molecular Biology and Genetics – Middle East Technical University, Turkey
2006 M.S. Molecular Biology – International Max Planck Research School, Germany
2011 Ph.D. Chemistry – Utrecht University, Netherlands

Selected Publications

Karagöz GE, Acosta-Alvear D, Walter P. The Unfolded Protein Response: Detecting and Responding to Fluctuations in the Protein-Folding Capacity of the Endoplasmic Reticulum. Cold Spring Harb Perspect Biol. Review 11:a033886, 2019
(PMID : 30670466) (PDF)
Acosta-Alvear D, Karagöz GE, Fröhlich F, Li H, Walther T, Walter P. The unfolded protein response and endoplasmic reticulum protein targeting machineries converge on the stress sensor IRE1. eLife 7:e43036, 2018
(PMID : 30582518) (PDF)
Karagöz GE, Acosta-Alvear D, Nguyen HT, Lee CP, Chu F, Walter P. An unfolded protein-induced conformational switch activates mammalian IRE1. eLife 6:e30700, 2017
(PMID : 28971800) (PDF)

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