Douglas Freyman
Alumni Postdoc
Selected Publications
- Ramirez U, Minasov G, Focia P, Stroud R, Walter P, Kuhn P, Freymann D. Structural basis for mobility in the 1.1 A crystal structure of the NG domain of Thermus aquaticus Ffh. J Mol Biol 320:783-99, 2002
- Peluso P, Herschlag D, Nock S, Freymann DM, Johnson AE, Walter P. Role of 4.5S RNA in assembly of the bacterial signal recognition particle with its receptor. Science 288:1640-3, 2000
- Schmitz U, Behrens S, Freymann D, Keenan R, Lukavsky P, Walter P, James T. Structure of the phylogenetically most conserved domain of SRP RNA. RNA 5:1419-29, 1999
- Freymann D, Keenan R, Stroud R, Walter P. Functional changes in the structure of the SRP GTPase on binding GDP and Mg2+GDP. Nat Struct Biol 6:793-801, 1999
- Keenan R, Freymann D, Walter P, Stroud R. Crystal structure of the signal sequence binding subunit of the signal recognition particle. Cell 94:181-91, 1998
- Freymann D, Keenan R, Stroud R, Walter P. Structure of the conserved GTPase domain of the signal recognition particle. Nature 385:361-4, 1997
- Schmitz U, Freymann D, James T, Keenan R, Vinayak R, Walter P. NMR studies of the most conserved RNA domain of the mammalian signal recognition particle (SRP). RNA 2:1213-27, 1996
- Bernstein H, Zopf D, Freymann D, Walter P. Functional substitution of the signal recognition particle 54-kDa subunit by its Escherichia coli homolog. Proc Natl Acad Sci 90:5229-33, 1993