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Notice: Function _load_textdomain_just_in_time was called incorrectly. Translation loading for the outreach domain was triggered too early. This is usually an indicator for some code in the plugin or theme running too early. Translations should be loaded at the init action or later. Please see Debugging in WordPress for more information. (This message was added in version 6.7.0.) in /nas/content/live/wlabdemo/wp-includes/functions.php on line 6114 Functional dissection of the signal recognition particle. - Walter Lab
Functional dissection of the signal recognition particle.
Siegel V, Walter P. Functional dissection of the signal recognition particle. Trends Biochem Sci 13:314-6, 1988 (PMID : 2856455) (PDF)
Abstract
Biochemical mutagenesis – alteration or removal of specific domains within a biological structure -followed by functional analysis, gives insight into structure-function relationships. We describe the analysis of the signal recognition particle, a ribonucleoprotein known to be required for the entry of most proteins into the secretory pathway, as an example of the strength of this approach.