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SRP–where the RNA and membrane worlds meet.

Walter P, Keenan R, Schmitz U. SRP–where the RNA and membrane worlds meet. Science 287:1212-3, 2000
(PMID : 10712156) (PDF)

Abstract

Working out how the signal recognition particle (SRP) of cells directs newly synthesized proteins destined for secretion to the endoplasmic reticulum (ER) has proved a gargantuan task. That task has just been made easier, as explained in a Perspective by Peter Walter and colleagues, by the solving of the crystal structure of the RNA-protein core of the SRP ( Batey et al.)

Article  – http://science.sciencemag.org/content/287/5456/1212.full


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