Kelly Crotty

Kelly Crotty

Alumni Graduate Student

kelly@walterlab.ucsf.edu

Scientific Interest

I am interested in how the cell post-transcriptionally modifies its protein expression profile in order to adapt to stress. This includes the selective translation of mRNAs encoding stress-response proteins as well as changes in mRNA degradation dynamics.

Current Research Interests

I am currently investigating how the truncated mRNA of BiP1, an ER-chaperone protein, is stabilized after loss of its polyA tail during ER stress in S. pombe.

Education

2008-2012 B.S. Biochemistry & Biophysics – Oregon State University, USA
2012-Present Ph.D Biochemistry & Cell Biology – University of California, San Francisco, USA

Selected Publications

Li W, Crotty K, Garrido Ruiz D, Voorhies M, Rivera C, Sil A, Mullins RD, Jacobson MP, Peschek J, Walter PProtomer alignment modulates specificity of RNA substrate recognition by Ire1. eLife 10:e6742, 2021
(PMID: 33904404) (PDF)

Li W, Crotty K, Ruiz DG, Voorhies M, Rivera C, Sil A, Mullins RD, Jacobson MP, Peschek J, Walter PProtomer alignment modulates specificity of RNA substrate recognition by Ire1. bioRxiv doi: https://doi.org/10.1101/2021.02.10.430655, 2021
(PMID: not available) (PDF)