Pascal Egea

Alumni Postdoc

pegea@mednet.ucla.edu

Selected Publications

Korennykh A, Egea P, Korostelev A, Finer-Moore J, Stroud R, Zhang C, Shokat K, Walter PCofactor-mediated conformational control in the bifunctional kinase/RNase Ire1. BMC Biol 9:48, 2011
(PMID: 21729334) (PDF)

Korennykh A, Korostelev A, Egea P, Finer-Moore J, Stroud R, Zhang C, Shokat K, Walter PStructural and functional basis for RNA cleavage by Ire1. BMC Biol 9:47, 2011
(PMID: 21729333) (PDF)

Korennykh A, Egea P, Korostelev A, Finer-Moore J, Zhang C, Shokat K, Stroud R, Walter PThe unfolded protein response signals through high-order assembly of Ire1. Nature 457:687-93, 2008
(PMID: 19079236) (PDF)

Egea P, Tsuruta H, de Leon G, Napetschnig J, Walter P, Stroud R. Structures of the signal recognition particle receptor from the archaeon Pyrococcus furiosus: implications for the targeting step at the membrane. PLoS ONE 3:e3619, 2008
(PMID: 18978942) (PDF)

Egea P, Napetschnig J, Walter P, Stroud R. Structures of SRP54 and SRP19, the two proteins that organize the ribonucleic core of the signal recognition particle from Pyrococcus furiosus. PLoS ONE 3:e3528, 2008
(PMID: 18953414) (PDF)

Egea P, Stroud R, Walter PTargeting proteins to membranes: structure of the signal recognition particle. Curr Opin Struct Biol 15:213-20, 2005
(PMID: 15837181) (PDF)

Chu F, Shan S, Moustakas D, Alber F, Egea P, Stroud R, Walter P, Burlingame A. Unraveling the interface of signal recognition particle and its receptor by using chemical cross-linking and tandem mass spectrometry. Proc Natl Acad Sci 101:16454-9, 2004
(PMID: 15546976) (PDF)

Egea P, Shan S, Napetschnig J, Savage D, Walter P, Stroud R. Substrate twinning activates the signal recognition particle and its receptor. Nature 427:215-21, 2004
(PMID: 14724630) (PDF)