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Ryan Dalton

March 12, 2015 By

Scientific Interest

The brain is composed of a multitude of cell types, far too many for any one accounting, and understanding how this diversity is generated is my overarching scientific interest. Particular diversity can be found in the sensory systems, where sensory neurons often employ complex and hierarchical gene regulatory programs to tightly define their stimulus receptive fields. To approach the question of how neuronal diversity is generated, I use molecular genetics and biochemistry to study the sensory systems of the mouse.

Former Lab Affiliations

2010-Present Dr. Stavros Lomvardas – Graduate Student, UCSF and Columbia University
2008-2010 Dr. Richard Goodman – Lab Manager, Vollum Institute at Oregon Health Sciences Institute
2007-2008 Dr. Zhong Yi – Visiting Scholar, Tsinghua University
2006-2007 Dr. Chris Doe – Lab Technician, University of Oregon
2004-2006 Dr. Joseph Pechmann – Undergraduate Research Assistant, University of New Orleans

Education

2006 B.S. Biology – University of Oregon,
2010-2015 Ph.D – University of California, San Francisco,

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Kelly Crotty

March 12, 2015 By

Scientific Interest

I am interested in how the cell post-transcriptionally modifies its protein expression profile in order to adapt to stress. This includes the selective translation of mRNAs encoding stress-response proteins as well as changes in mRNA degradation dynamics.

Current Research Interests

I am currently investigating how the truncated mRNA of BiP1, an ER-chaperone protein, is stabilized after loss of its polyA tail during ER stress in S. pombe.

Education

2008-2012 B.S. Biochemistry & Biophysics – Oregon State University, USA
2012-Present Ph.D Biochemistry & Cell Biology – University of California, San Francisco, USA

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Min Cho

March 12, 2015 By

Scientific Interest

Cancer biology, drug resistance, cellular stress responses, protein-protein interactions, synergistic gene activation, genome wide and sub-genome wide genetic interaction screening platforms

Current Research Interests

Sub-genome wide shRNA screening of multiple myeloma; dissection of potential drug protection and sensitization pathways in lymphoid cancers

Former Lab Affiliations

2008-2009 Cammie Lesser, M.D., Ph.D. – Undergraduate Researcher, Harvard Medical School/Massachusetts General Hospital, Department of Infectious Diseases
2009-2011 Frank Naya, Ph.D. – Graduate Researcher, Boston University, College of Arts & Sciences, Department of Biology
2011-2012 Mark Schlissel, M.D., Ph.D. – Lab Manager/Staff Research Associate , University of California at Berkeley, Department of Molecular & Cell Biology
2012-2013 – Research Associate II, Bio Architecture Lab

Education

2011 B.A. Biochemistry & Molecular Biology – Boston University, USA
2011 M.A. Biotechnology – Boston University, USA

Links

LinkedIn


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Diego Acosta-Alvear

March 12, 2015 By

Current Position

Assistant Professor
Department of Molecular, Cellular, and Developmental Biology
University of California Santa Barbara
daa@lifesci.ucsb.edu

https://labs.mcdb.ucsb.edu/acosta-alvear/diego/

Scientific Interest

Wiring of the unfolded protein response in normal cells and in disease.

Current Research Interests

Protein-RNA interactions operating during the ER stress response employing next generation sequencing coupled to biochemistry and cell biology methods. The re-wiring of the unfolded protein response in cancer cells employing ultra complex shRNA libraries to discover genetic vulnerabilities.

Former Lab Affiliations

2003-2008 Dr. Brian Dynlacht – Graduate Student, New York University

Education

2008 Ph.D Biomedical Sciences – New York University,
2005 M.S. Biomedical Sciences – New York University,
2002 M.S. Biological Sciences – Universidad de los Andes,
2001 B.S. Biological Sciences – Universidad de los Andes,

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Peter Walter

March 12, 2015 By

 About Peter

Peter Walter’s Biography
Peter’s UCSF Profile

Selected Articles

Harnessing Serendipity  by Esther Landhuis
Along unpredictable paths to discovery, Peter Walter has maintained a sure-footed approach – to the science as well as to the people he mentors …

This article features videos of interest including:

  • “Squeezing Time for Art” – Peter shares some of the pieces of art he has created and the stories behind them.
  •  “What is the Unfolded Protein Response” – Curious about the Unfolded Protein Response? Learn more from this video.
  • “The 2015 Vilcik Prize in Biomedical Science Video” – The Vilcek Foundation produced this video which captures a bit about a day in the life of Peter and our lab. We thank them for their generosity.


Walking Along the Serendipitous Path of Discovery by Peter Walter

Students entering graduate school often ask for the “recipe for success.” Yet looking back at the events that shaped my own career, both personal and scientific, I continue to be amazed by the convoluted paths, which are neither linear nor predictable. This is a difficult message to transmit to those embarking on a research career, and it invariably prompts the next question: “So you say that our success in science will be determined by dumb luck?” Not so—it’s serendipity, a word that much better describes our path to discovery. It is not uncommon that initially disappointing turns lead to unexpected outcomes that then miraculously align to appear as a progression of incredibly good fortune …


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